Questions about depression medications

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Donna&Scott

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Have any studies been conducted on the effects of Prozac or other depression medications at depth/pressure? In our NAUI video they mention that the effects of prescription drugs on divers is not known. The doctor at this point knows of no reason why they could not be taken during diving, however he is going to talk to the manufacture of Prozac to see if they know of any reason.
 
Dear Donna and Scott:

This question should be referred to the physicians on the Medical Forum of ScubaBoard. They could possibly have some information on Prozac and similar medications.

As far as decompression physiology is concerned (that is, will this medication increase gas bubble formation), I do not know of any problems. This does not say that other problems might exist, but for this, one should ask a clinician.

Dr Deco
 
Thank you for the information and moving the question to the correct forum. Hopefully we will be able to get some information.
 
There is little in the literature about diving and psychoactive medications of any kind. What we have to do is to extrapolate known dangers to divers in general with the effects and possible side effects of these drugs. We published several articles in 'Alert Diver', a publication of DAN, Divers Alert Network; Psychological Issues in Diving, DAN's 'Alert Diver', Sept-Dec, 2000) . This is reproduced in our web site at http://www.scuba-doc.com/psych.htm .

For example; seizure activity is a major risk for divers as it invariably leads to drowning. This known due to diving accidents that have occurred with the seizures of oxygen toxicity. Therefore, seizure activity is a contraindication to diving and medications that have a risk of causing seizures are also dangerous in this regard. (Prozac is one of these drugs). This includes a low but constant 0.2% risk for all anti-depressives and also other medications, including the anti-malarial, Lariam and bupropion (Zyban, Wellbutrin).
http://www.scuba-doc.com/epildv.htm

In addition, patients are warned not to take Prozac while operating machinery or driving. We have to also be aware of the possible additive sedative effect of nitrogen at depth or 'nitrogen narcosis', a real threat for divers who go below about 90 feet sea water. We have no literature on this subject. Only just recently do we have a RCT (random controlled study) of the drug 'Dramamine', that indicates a significant decrease in cognition (awareness)in divers (dry dives in a chamber). It is probable that if good studies were done with all medications, that we would find many that alter the ability to function underwater.

Diving is a multi-task sport, requiring constant concentration and attention to minutae. Any alteration in sensorium is dangerous to the diver and to his 'buddy', to the divemaster and to all other divers on the dive excursion.

In summary, one needs to consider the following guidelines to use in considering the relationships between drugs and diving:
---Consider the condition/illness/disease for which the medication is being given. Depression is one of the conditions that some diving doctors feel constitutes a contra-indication to diving. However, as with most 'fitness to dive' considerations, clinical judgement needs to be used.

---Are there any effects of the drug that alter consciousness or cause alteration in decision making ability? Are combinations of drugs additive in their effects, particularly when taken at depth with the added effects of nitrogen? .

---Consider complex relationships between drugs, the individual, other medications, diet and the conditions for which the drugs are taken.

These guidelines are particularly important in deciding if a person can be certified to dive while taking several medications - the usual situation with psychiatric patients.
 
Scubadoc's comments are, as usual, very appropriate and correct.

I can't tell you what your risks are. I can tell you that I have had patients that I have evaluated and felt were indeed fit to dive on Prozac.
There is enormous variability from person to person in their response to medications, and advice needs to carefully tailored to the individual diver, and could vary from month to month (or potentially day to day.)
Ask the question of a doctor that understands diving and its demands, and be cautious about accepting a response that comes without some very carefully asked questions before clearing or restricting you. You are asking for a medical judgment, and this is an area of dive medicine that doesn't have any "pat" or automatic answers.
Good luck, and I hope you are cleared to dive.
Dive safe and alert,
John
 

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