beche de mer
Contributor
Hope this question hasn't been asked before. Apologies if it has.
I'm a little confused about how a patent foramen ovale (as opposed to atrial septal defect) can predispose to DCI.
I can see that a PFO would allow direct access of bubbles in the venous circulation to the arterial side, but given that left atrial pressures are higher than right atrial pressures, how can flow occur along an uphill pressure gradient and, in any case, would not the "flap valve" remain closed?
Or does right atrial pressure exceed left atrial pressure during left atrial diastole?
Thanks.
I'm a little confused about how a patent foramen ovale (as opposed to atrial septal defect) can predispose to DCI.
I can see that a PFO would allow direct access of bubbles in the venous circulation to the arterial side, but given that left atrial pressures are higher than right atrial pressures, how can flow occur along an uphill pressure gradient and, in any case, would not the "flap valve" remain closed?
Or does right atrial pressure exceed left atrial pressure during left atrial diastole?
Thanks.