Oxygen Window?

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Kendall Raine:
Do you know what this maximum is...
One thought...

"Noteworthy is the fact that the oxygen pressure in arterial blood can be raised to about two Atm (15 psi gage) or some 1500 mm Hg without a rise of more than several hundred mm Hg of oxygen in mixed venous blood. Since oxygen becomes abruptly toxic above this level, there is a practical limit to the size of the oxygen window." - Behnke. (1967) The isobaric (oxygen window) principle of decompression. In: The New Thrust Seaward. Trans. Third Marine Tech. Soc. Conf. 5-7 June, San Diego. Washington, DC: Marine Tech. Soc.

The isobaric (oxygen window) principle of decompression.
Behnke AR, 1967
RRR ID: 4029

Kendall Raine:
...is there a relationship between the maximum and the choice of 60 feet as the first O2 stop in recompression protocol?
Time to get in the 'way-back' machine...

"Owing to the toxic effects of breathing oxygen under pressure the time of exposure is limited. It has been shown by Behnke, Forbes and Motley (1935) that pure oxygen under a gauge pressure of 30 pounds can be tolerated for about 3 hours before the toxic effects are manifested by contraction of the visual field, rise in blood pressure and increase in pulse rate. Behnke, Johnson, Poppen and Motley (1935) have shown that when the oxygen pressure is increased to 45 pounds syncope or a convulsive seizure may occur. It would, therefore, be wise to limit the pressure of the oxygen breathed to 30 pounds. At this pressure there can be little doubt that all, or nearly all, the nitrogen bubbles will be absorbed in severe cases of compressed-air illness." Behnke and Shaw 1936

Behnke et. al. (1936) THE CIRCULATORY AND RESPIRATORY DISTURBANCES OF ACUTE COMPRESSED-AIR ILLNESS AND THE ADMINISTRATION OF OXYGEN AS A THERAPEUTIC MEASURE. Am J Physiol 114: 526-533
This and the other referances above may be found in the Am J Physiol.

The information above is also referenced in: Behnke and Shaw. (1937) The use of oxygen in the treatment of compressed-air illness, U.S. Nav. M. Bull. 35: 61-73.
--I will not have my hands on a copy of this until tomorrow at the earliest.

The 1937 Behnke paper is the reference from:
Physiologic Factors Underlying the Prevention and Treatment of Decompression Sickness.
Van Der Aue et. al. 1945
RRR ID: 3313, NEDU ID: AD0756182
 
Amazing Gene. I thought the work was more recent, B&E give it to the 1960s, but clearly Behnke knew of it as far as the 1930s. Rubicon is an amazing resource.
 

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