Nitrox is especially useful if:
1) You are subject to one, or more,
predisposing factors for DCS. It enables a higher degree of conservatism, if dived as per air profiles/NDLs.
2) You complete square profile dives, and cannot effectively extend bottom time through multi-level dive profiles via a computer.
3) You complete multi-day, repetitive dives and find that successive dives suffer from NDLs that prematurely shorten your desired bottom time.
4) You primarily dive with other divers who use nitrox.
Nitrox is not especially useful if:
1) Your bottom time is primarily dictated by your air consumption and you rarely, if ever, approach no-deco limits.
2) You do not have a reliable, convenient and cost-effective access to nitrox supply (rare nowadays).
3) Your dive buddy/group isn't using nitrox.
4) You are convinced that you are immune to DCS.
IMHO Nitrox is perfect for:
1) Liveaboard trips and other intensive diving periods, where you complete repetitive dives, including deep, over several days.
2) Wreck diving in the 80-130' range.
3) Divers with above-average air consumption and/or access to high capacity cylinders or doubles/sidemount.
4) Any combination of the above.
The 'restorative' effects of nitrox (i.e. feeling less tired after dives) are entirely unproven by research. However, many divers do testify that they feel less fatigued after diving when nitrox is used. That may be a placebo effect. However, if it makes you
feel better, for whatever reason, then it has a value I guess.
Post-dive fatigue/lethargy/tiredness/aches may be indicative of non-symptomatic (micro) bubbles. We all get these to a varying degree. Personal physiology, dive profiles/schedules and other conditions/pre-disposing factors account for the variance. Divers can get 'used' to that feeling after dives - it becomes the norm. When they use nitrox, if not pushing the adjusted NDLs, they are benefiting from less nitrogen absorption - less post-dive (micro) bubbles... hence, they feel 'fresher'. Actually, they just feel normal... but, in doing so, notice that the 'usual' symptoms are reduced.