I started using air-integrated computers in the early nineties with the Genius computer. Normally no problems, only when the battery of the transmitter ran out of juice.
After that, I got the Scubapro Air-Z, then Air-z Nitrox and Air-Z O2, which I still keep for back-up. Under normal use (no strobes) practically no interruption in transmission, though I kept analog for safety.
Since moving up to Galileo Sol, which has a stronger transmitter and a better signal (new type of transmitter, the same as for Smart/Smart Pro/Luna) never had any signal problems. So now decided to leave out analog. I will though probably also attach an analog gauge as safety backup when going trimix/tec. The Sol has a warning for weak transmitter battery, which previous models did not have.
On live-aboards you'll have to teach the crew not to grab the tanks by the transmitters (as they usually tend to do) to avoid damage. There is no interference from various Sol transmitters close to each other, as each has its specific pairing code; you can however check also your buddies data, if he/she is in close range (max. 1,5-2 meters) with a second paired transmitter.
Conclusion: there have been possible problems in the past from weaker signals (battery, transmitter position or strobe related), which nowadays could/should be avoidable.
By the way, on my last holiday I noticed a diver with a high pressure tube/pressure gauge that was leaking air over its entire length, ready to blow up. So they can fail as well.
Air-integrated computers are no worse or better than analog devices, both can fail , both rely in the end on quality and maintenance. But air-integration offers advantages that analogue gauges cannot offer (RBT calculation, for example).
It also offers (e.g. through the programme Smarttrak) the possibility to analyse your air consumption during various phases of the dive, as well as to check other parameters, which help to make you aware of your dive behaviour and to learn from experience. But in the end, it all comes down to personal preference. And mine is definitely for air-integrated computers.