My friend suggested I look over the Cootwo for signs of cracked solder joints, but that will require that I do some work to extricate the board that is held in not with screws, but with melted plastic standoffs. His theory is that there is voltage leakage from the o2 circuit that is bleeding into the CO side, and it might be the result of a damaged trace or cracked solder joint.
You also trying to transpose the technology for measuring one analyte (O2) to the technology for measuring another (CO). Don't do that.
I agree with these views, you can imagine a number of issues with bad earth paths or poor power supply design that will make the two readings interfere. I doubt the device was designed for high O2.
It seems unlikely that CO in pure O2 will be an issue, first it would have to be boosted with a badly maintained booster, secondly you are breathing it at a much lower pressure. Has it ever happened that this has resulted in CO poisoning?