Kevrumbo
Banned
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So what? --study is 35yrs old?? It's still qualitatively very relevant to the OP.Kevrumbo,
You realize that you are quoting a biomedical study that is 35 years old.
Here is the abstract of that study:
Undersea Biomed Res. 1978 Dec;5(4):391-400.
Roles of nitrogen, oxygen, and carbon dioxide in compressed-air narcosis.
Hesser CM, Fagraeus L, Adolfson J.
Abstract
In an attempt to determine the roles of nitrogen, oxygen, and carbon dioxide in compressed-air narcosis, the effects on performance (mental function and manual dexterity) of adding CO2 in various concentrations to the inspired gas under three different conditions were studied in eight healthy male volunteers. The three conditions were: (1) air breathing at 1.3 ATA; (2) oxygen breathing at 1.7 ATA; and (3) air breathing at 8.0 ATA (same inspired O2 pressure as in (2)). By relating performance to the changes induced in end-tidal (alveolar) gas pressures, and comparing the data from the three conditions, we arrived at the following results and conclusions. A rise in O2 pressure to 1.65 ATA, or in N2 pressure to 6.3 ATA at a constant high PO2 level, caused a significant decrement of 10% in mental function but no consistent effect on psychomotor function. A rise in end-tidal PCO2 of 10 mmHg caused an impairment of approximately 10% in both mental and psychomotor functions. The results suggest that, at raised partial pressures, all three gases have narcotic properties, and that the mechanism of CO2 narcosis differs fundamentally from that of N2 and O2 narcosis.
Roles of nitrogen, oxygen, and carbon di... [Undersea Biomed Res. 1978] - PubMed - NCBI
SeaRat
The above is the Meyer-Overton hypothesis put forward in 1899–1901, and is still current & basic oft-cited reference/textbook material for Recreational to Technical Scuba Courses & Training (see PADI Encyclopedia of Recreational Diving Ch.5/p22). . ."The Meyer-Overton hypothesis states that narcosis happens when the gas penetrates the lipids of the brain's nerve cells. Here it apparently interferes with the transmission of signals from one nerve cell to another. Exposure to nitrogen-oxygen mixture at high pressure induces narcosis, which can be considered as a first step toward general anesthesia. . . and narcotic potencies of inert gases are attributed to their lipid solubility."
To Recap:
Taken from Undersea Biomedical Research, Vol 5, No. 4 December 1978 Hesser, Fagraeus, and Adolfson:
"Studies on the narcotic action of various gases have shown that the ratio of narcotic or anesthetic potency of CO2 and N2O approximates 4:1, and that of N2O and N2 30:1. From these figures it can be calculated that CO2 has at least 120 times the narcotic potency of nitrogen. Our data would suggest that the narcotic potency of CO2 is even greater, i.e., several hundred times as great as that of nitrogen."
Dr. Bookspan is the author of Diving Physiology in Plain English and various medical board review courses for hyperbaric medicine.
"Carbon dioxide retention is now viewed as a contributor to oxygen toxicity and nitrogen narcosis, suspected as a contributor to decompression sickness, and implicated in incidents of underwater confusion and loss of consciousness."
Deep Air with increased Gas Density & Work-of-Breathing; then throw in Physical Exertion or a Stress Condition, resulting in overbreathing the regulator --all leading to the Vicious Cycle of CO2 Retention and sudden Narcosis. Can result in severe cognitive impairment at depth or worst case stupor and ultimately unconsciousness. . . the issue here is to break this vicious, panic inducing & building feedback cycle of Narcosis and CO2 retention by immediately aborting the dive. Ascend properly & smartly with your buddy to your safety stop, deploy your SMB as needed, and surface.
Also implicating the insidious nature of CO2:
Lanphier and Camporesi. Chapter 5. Respiration and Exertion, The Physiology and Medicine of Diving:
1. Higher Inspired Oxygen (PiO2) at 4 ata [30m/100'] (404 kPa) accounted for not more than 25% of the elevation in End Tidal CO2 (etCO2) above values found at the same work rate when breathing air just below the surface.
2. Increased Work of Breathing accounted for most of the elevation of PACO2 (alveolar gas equation) in exposures above 1 ata (101 kPa). . .
3. Inadequate ventilatory response to exertion was indicated by the fact that, despite resting values in the normal range, PetCO2 rose markedly with exertion even when the divers breathed air at a depth of only a few feet.
further references to support the quote above:
Lanphier. Nitrogen-Oxygen Mixture Physiology, Phases 1 and 2. NEDU Report 1955-07. RRR ID: 3326
Lanphier, Lambertsen, and Funderburk. Nitrogen-Oxygen Mixture Physiology - Phase 3. End-Tidal Gas Sampling System. Carbon Dioxide Regulation in Divers. Carbon Dioxide Sensitivity Tests. NEDU Report 1956-02. RRR ID: 3327
Lanphier. NITROGEN-OXYGEN MIXTURE PHYSIOLOGY. PHASE 4. CARBON DIOXIDE SENSITIVITY AS A POTENTIAL MEANS OF PERSONNEL SELECTION. PHASE 6: CARBON DIOXIDE REGULATION UNDER DIVING CONDITIONS NEDU Report 1958-07. RRR ID: 3362
Lanphier. Nitrogen-Oxygen Mixture Physiology. Phase 5. Added Respiratory Dead Space (Value in Personnel Selection tests) (Physiological Effects Under Diving Conditions). NEDU Report 1956-05. RRR ID: 3809
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