Dr Deco,
Somewhere on your forum I am sure there is a thread listing the atmospheric pressure at various altitudes but I cannot find it.
However Bengal asked an interesting question.
The point I was making, (my physiology training keeps raising its ugly head) is that even when you breath 100% oxygen on the surface the alveolar pp O2 is not 1 bar. It is 1 bar less the saturated water vapour pressure at 37 degrees C AND the pp CO2, which is normally about 40 mmHg, I believe.
In healthy lungs the blood in the pulmonary circulation equalises with the pp O2 in the alveoli, not in the airways.
If 100% oxygen is breathed on the surface the airway pp O2 is 760 mmHg - 48 mmHg = 712 mmHg or 0.93 bar but carbon dioxide is also present in the alveoli to dilute the pp O2 even further by 40 mmHg to 672 mmHg or 0.88 bar
When air is breathed the inspiratory pp O2 is 0.21 bar; 0.21 x 760 mmHg = 159 mmHg and the alveolar pp O2 is 0.21 x 672 = 141 mmHg (0.21 x 0.88 = 0.17 bar).
If I remember correctly 1 atmosphere is 29 inches of water so 6 inches of water is 0.2 bar (157 mmHg). Thus your high altitude fast jet pilots are breathing oxygen with a partial pressure very close to the pp O2 of air at the surface.
Let's take the example of a fast jet pilot having to eject into a very thin atmosphere a quarter normal of 0.25 bar (3.7 psi) WITHOUT oxygen.
He is beathing air at 190 mmHg with with an inspiratory pp O2 of 0.21 x 190 = 40 mmHg (0.05 bar) but what about water vapour and carbon dioxide?
This guy's alveolar pp O2 is 0.21 x (190 - 48-40) = 21.5 mmHg.
The oxygen reaching his circulation is reduced to about a half that available in the outside air due to the water vapour and carbon dioxide produced by the body.
At this partial pressure the arterial haemoglobin is only about 30% saturated.
As Piscean has shown elswhere, at
http://www.mtsinai.org/pulmonary/ABG/PO2.htm the blood of a healthy fit male contains up to 15 g of haemoglobin per decilitre, each gram of which can carry 1.34 ml of oxygen.
This pilot's arterial blood will carry only 15 x 1.34 x 30% = 6 ml of oxygen per decilitre all of which will be needed for metabolism.
I suspect that not all of this oxygen can be freed from haemoglobin for metabolic neeeds at the tissues so this pressure could be well below the minimum required to support life.
I thought it was generally accepted that a ppO2 of less than 0.1 bar is deadly, which is why the BSAC do not advocate the use of any diving mix with a FO2 of less than 0.12 since it would lead to unconciousness or death if breathed on, or close to, the surface.
No doubt a physiology text book would provide a definitive answer.
