This is incorrect (for tissue loading). Having done a few deco dives at Jefferson Lake(11,000' driving from 5,500') your shearwater shows tissue loading on arrival. Interestingly driving from Denver over a pass to get there usually I have GF99 still at 0, but can see loading on the graph. While a buddy driving up from Colorado Springs with a direct ascent has seen GF99 as high as 30% on arrival.
I believe Shearwater tracks tissue loading based on ambient pressure continuously even when the device is turned off. I recommend you put the battery in before making an ascent to an altitude dive.
Given the navy warnings quoted by
@boulderjohn we use extremely conservative GFs 35/45, and usually stay on O2 until our surf GF is very low or zero.