Kathy: I am going to jump in here because I still cannot figure out how to post...if you had to decide between staying on the East end...or at the point...which would you choose?
Thank you
I think that depends on what you like to do on vacation, how much diving you want to do, what time of year that you plan to travel, how much money you want to spend, and how willing you are to devote vacation time to driving on the left side of the road.
I'm not trying to be evasive, but I am not sure that there is a "one size fits all" answer to this question.
If you are traveling with non-diving companions and/or you love to spend time at the beach and/or enjoy sampling gourmet foods on vacation - then you should probably stay in the Seven Mile Beach area, or just north of it in West Bay near Lighthouse Point.
If you really enjoy shore diving, then West Bay north of 7MB is a good choice because you have easy access to the most popular shore dives on Cayman.
If you are traveling in winter and spring, you have increased chances of getting winded out on the East and North sides. There's no guarantees about the weather, but you have better chances of calm diving on the West side during those months, and in the summer you have less chance of being hit with an influx of sargassum seaweed on the west side.
Over the years I have had some really great dives on the West side but some of my most memorable dives on GC have been on the dramatic East End and the North wall. If you decide to stay on the East End you will be rather far away from many the popular restaurants and attractions of GC - about 45 min to 60 minutes - and traffic can be very bad during rush hours, so you should be prepared to spend most of your time on the East End. That's not really a hardship (there is life on the East End and Northside! But it is not for everyone.)
If you are going to GC for an "eat, sleep, dive, and relax" vacation then someplace like Compass Point with Ocean Frontiers on the East End would probably be a very good choice for you.
If you want to increase your chances of calm weather, easy shore diving, and access to more topside activities - and still enjoy some very good diving with the best chances of calm conditions, then staying in the 7MB area or West Bay north of 7MB, at someplace like Lighthouse Point/DiveTech would likely be a good choice for you.
And budget is also a factor, the closer you are to 7MB the more expensive things tend to become - especially food and lodgings. The more remote areas are cheaper but you have to rent a car. I would probably rent a car in most areas of GC anyway, but if you don't want to rent one then you should stay in Central 7MB - the most developed and expensive district.
There are lots of dive sites and many dive ops on Cayman and I haven't sampled all of them, but you can find a wide range of locations, venues, and prices to best meet your needs, budgets, and tastes.
Some of the very best diving I have done in Cayman has been on Bloody Bay Wall in Little Cayman which is a very rural place that may be reached by taking a half-hour ride on a tiny plane.
The most dramatic and impressive topography I have enjoyed in Cayman has been on Cayman Brac, which also has some great dives but it is like LC in that it is very rural and it's not easy to get there.
Cayman's motto should be "we have something here for everyone!" I suggest coming back several times to try and enjoy all of the faces of Cayman - that's what I do!