I wore the patch (Transderm Scop) and generally had no problems. The boat did rock a bit more than I expected (maybe more so for me as I had the quad room upstairs), but this was only my second liveaboard (first being the Aqua Cat, which might be a bit more stable). In any case, enjoy!
P.S. If you do decide to go with the patch, whatever you do, don't touch the patch and then your eyes without washing your hands multiple times! The medicine in the patch can cause your pupils to dilate to enormous sizes. This happened to me the first time I wore it (on a cruise a few years ago).