A few comments from a diving pharmacist/toxicology specialist:
1. I would suggest that if you take Sudafed (pseudoephedrine), you take the extended-release tablets, as they are much less likely to wear off during your dive. Typically, the extended-release tablet works for roughly twelve hours.
2. Sudafed, and other systemic decongestants are mild central nervous system stimulants. If you feel that you will need to take the drug before diving, you may want to limit your caffeine intake.
3. If you're treating nasal stuffiness, you may want to consider a topical decongestant (nasal spray). Again, use the long-acting version. Oxymetazoline (Afrin, Sinex Long Acting) will keep your nasal passages open without affecting your central nervous system.
4. Note that Sudafed is a product line that includes many combination products, many of which contain antihistamines, such as diphenhydramine (benadryl). If you need the decongestant effect, use one that only contains pseudoephedrine.
Of course, it goes without saying that it is best to dive without taking any medications, as medications are not tested under the conditions typically found during a dive. That being said, if you follow the above guidelines, you will minimize the chance of a reverse block.
Best wishes and safe ascents,
Grier