DivingDoc
Contributor
Originally posted by DocVikingo
Dramamine now comes in two flavors, Dramamine Original Formula (dimenhydrinate) & Dramamine Less Drowsy Formula (meclizine). Both make many folks drowsy, although less so with the latter. Research has indicated that the former is not a good mix with scuba.
Mescolor is an antihistamine/decongestant/drying agent that contains chlorpheniramine, pseudoephedrine & methscopolamine nitrate (Transderm Scop uses straight scopolamine within its delivery system). Mescolor might be helpful against mal de mer, but I certainly wouldn't recommend it for scuba unless the diver also had signs/symptoms of allergic rhinitis, sinusitis and/or a common cold.
Didn't know Dramamine came in two flavors -- just took a look at the ingredients a few years ago one day and realized they had changed. The active moity of dimenhydrinate is diphenhydramine (Benedryl). Diphenhydramine, as the makers of Allegra like to point out, has been shown to cause more impairment of driving performance than alcohol (Allegra causes no more impairment than placebo).
I did not mean to imply that the methscopolamine (scopolamine-like agent) in Mescolor was the same as the scopolomine used in Trans-derm Scope (though, now that I look at my grammar, it does read like that). Personally, I don't prescribe it, though my some of my colleagues do. I don't like methscopolamine because it can cause confusion. I remember also some reports 10-12 years ago which reported hallucinations in connection with Trans-derm Scope. However, I brought it up because, since it is similar to scopolamine in effect, it could maybe work for sea sickness. Injectable scopolamine, incidentally, as you probably know, was used as "truth serum" during World War II, and has been used pre-operatively (at least in the past) as an agent to dry-up mucous and cause amnesia for the events of the surgery.
I was not recommending either for SCUBA diving -- just for sea sickness.
I'd be interested to know, however, why dimenhydrinate, but not meclizine, was bad during SCUBA diving. If it was because of the mental impairment/drowsiness, then why is meclizine OK, since it still does cause drowsiness?