Hello Readers:
PreOxygen
As others have already indicated, there is not a great advantage to inert gas washout prior to a dive. The driving pressure is less than one ATA during the oxygen prebreathe (washout), but it is at least 2 or 3 ATA for the inert uptake during the dive.
I would guess that it is better to save the oxygen for an emergency. If you wish safety, shorted the bottom times, lengthen the surface interval, and avoid stressful physical activity.
Research
Below are a couple of recent research studies involving preoxygenation [I was involved with ref 1.]. Both administered the oxygen hours before the dive, and the authors indicated that biochemical mechanisms were playing a role [ref. 1] or nuclei reduction was involved [ref. 1 and 2]
Dr Deco :doctor:
References :book:
[1.] Butler BD, Little T, Cogan V, Powell M. Hyperbaric oxygen pre-breathe modifies the outcome of decompression sickness. Undersea Hyperb Med. 2006 Nov-Dec;33(6):407-17.
[2.] Katsenelson K, Arieli Y, Abramovich A, Feinsod M, Arieli R. Hyperbaric oxygen pretreatment reduces the incidence of decompression sickness in rats. Eur J Appl Physiol. 2007 Nov;101(5):571-6. Epub 2007 Aug 3.