@stuartv I totally agree with you from a physics point of view, when it comes to ongassing, offgassing and partial pressures.
I would be careful with such a statement, my medical knowledge isn't enough to answer to that.
There's a biological part as well and I'm not sure if (unused) oxygen is simply returned from the tissues to the veins and to the lungs for off-gassing.
In order to understand this think to the blood as a conveyor belt. It picks up oxygen at the lungs and brings it all around the body. If oxygen is needed it is used by the cells, if not it stays on the conveyor belt.
When the coveyor belt goes back thru the lungs, if there is space available on the conveyor belt additional oxygen is loaded, otherwise the conveyor belt keeps going.
The only case oxygen might be released (but it wont because it would have been used well before returning to the lungs) would happen if you reduce ambient pressure and make the plasma supersaturated ... when in the lungs. it does not happen.
The conveyour belt has two ways of carrying oxygen:
- slots that can carry one O2 molecule bound to Fe in hemoglobin (the amount that can be carried is fixed and does not vary with pressure, only depends on how many red cells you have)
- free dissolved in plasma (amount is function of pressure the higher the more dissolves in plasma).
At high pressure all the slots are and remain occupied by O2 and the exchanges happen with the O2 in plasma. At low pressure the plasma carried oxygen is insufficient to satisfy metabolic needs and the hemoglobin bound O2 is also used.
Very approximative but I hope I gave a model to understand it.
As others before me said, the amount of oxigen used by the body at a given effort level does not vary. Meaning: the number of moles (mass) of O2 used in a time unit stays constant. A mole of O2 contains the Avogadro number of molecules (the molecules are used in the chemical reactions and therefore the number of those used change only if you i crease your effort or need to generate more heat to stay warm). If you want to know how many liters or bar (or whatever unit of your choice) use the PV=nRT gas state equation where n is the number of moles P is pressure V is volume and T is absolute temperature. R is a constant that depends of the unit used.
Basic 10th grade physics and chemistry.
Cheers