Here's a way to see how they work differently, maybe:
With the reg out of your mouth, and the lever to +, a push on the purge button should result in a free flow that won't stop until their is some back pressure (a single finger 'shushing' the reg should do). That + or - allows a vane inside the reg to either create flow that continues to give until back pressure is applied, or to make the flow stop when suction stops.
The winding knob increases tension on the spring, which make the 'cracking effort' higher or lower. Why would one ever want a reg to be 'harder' to breathe? Well when one is facing into a current there might be times when one wants the cracking pressure to be higher so as to stop the surging that the flow of water can cause. Plus for fine control when spending a good deal of time head down.