I guess Occam's razor would indicate to me that the simplest answer, one that bypasses all theology, satisfies all my needs. But I do see Theology as a loss, it is an attempt to reduce the wonder of the universe to a scale that some as-yet half evolved apes can grock ... that's lèse majesté (or hubris if you prefer)...
William of Ockham (Surrey, England 14th Century A.D.) came up with the KISS principle for philosophy, yes. A good principle, indeed. I use it every time I plan and execute a technical dive.
He also was a devout Franciscan friar, although one who had serious misgivings about the current Roman Pope of his day. His radical ideas, according to my philosophy survey book, included (1) a Pope should be subject to impeachment, and (2) Kings and royalty should be subject to impeachment as well.
I would categorize him as a skeptical pragmatist. He lived during a time that philosophers tried to synthesize Greek thought with Medieval church dogma.
He is not quite an existentialist, as you seem to be, Thal. But he did do a lot of thinking for himself, which made him unique for his day.
I myself have no problems integrating theology with science. It is really not hard to do, given that we truly know so little about either. All of our science is mere theory, justified by various levels of model demonstrations. And all of our religion is dogma based on the writings of ancient sages (nabi in Hebrew; prophetoi in Greek).
And KISS is a universal law, in my view. It is one of the first things anyone is taught in military or naval science.
I have found in reading history that Herodotus is the first ancient writer who attempts to be unbiased and fair in his reporting. That's why I date the origin of science to him. His was the science of journalism and early sociology. He lived shortly after the second Greek-Persian war, the one of Salamis & Platea fame.
Thusydides came along right after him and chronicled the Athenian-Pelopponesian War, and refined the process by leaving out all allusions of mythology, gods, and goddesses. For that, some scholars give him credit as the first true scientific journalist.
Either way, these two were the first. The date was the 5th Century B.C.E.
The previous writers were Homer of Illiad fame and Moses of Old Testament / Torah fame. And both of their writings involved a lot of gods.