Bryan>>>>"Yes and no. Mutation is the source of new variability, but the rest of evolution doesn't rely on that"
So evolution is just a change in allele frequencies then.
No. Changes in allele frequencies are one potential
product of evolution, not evolution itself.
Products of evolution include:
1) New genes
2) New alleles
3) Change in frequency, or elimination, of genes
4) Change in frequency, or elimination, of alleles
5) Stasis (no change)
6) Reorganization (shuffling) of the genome
7) Duplication of genes
8) Changes in gene expression, without formation of a new allele
9) Neutral mutations
10) Expantion/contraction of non-encoding DNA
11) Horizontal gene transfer
12) Nearly any combination of the above (obviously 5 cannot occur in conjuction with the others)
I'm sure I'm missing a few potential outcomes there, the list seems short to me...
Evolution is something quite different altogeather. It is either:
1) The process which produces the above effects, via mutation, selection and drift, or
2) The scientific thoery which explains why we see #1 occuring.
I would tell you that "the rest of evolution," as you state it, is nothing more than natural selection occuring on already present genes.
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That the bulk of scientific evidence would show that you are wrong. We know, for a fact, that each and every human on this earth carries an average of 3.75 point mutations not found in their parents. Likewise, more recient technology has allowed us to characterize the number of a different type of mutation, called an indel. Due to the newness of this technology we don't have a wide-spread screen of the human population, but small studies have found that the average joe has 7-12 indels not found in their parents. The rates in which we humans form other types of mutation - chromasomal reorganizations, gene duplication, etc - is also being characterized. We know the later forms of mutation happen often enough to be observed frequently "by accident"; the only outstanding question is exactly how often is "often". Heck, even selection is frequently been observed - the arise of HIV-resistant phenotyppes amoung Ughandan hookers being a new-ish example.
Likewise, the formation of new alleles, genes, and yes, even species has been directly observed by science. In fact, the first proven evolutionary events were speciation events - something which drove a counter theory (called mutationalism) for many decades. We've observed new genes and alleles form in nature, seem them be selected, even driven the whole process artificially in the lab, and characterized those kinds of changes in, and inbetween, tens of thousands of species.
The simple reality is yes, we do mutate. And those mutations undergo selection. That is not opinion, that is fact, based on numerous scientific investigations.
Again, the focus of the debate is over mutations occuring in a single-celled prokaryote (the simplist of living things according to Gould) eventually evolving, over millions of year, into a human (to just go ahead an jump to the crux, I suppose)
Hardly. The debate is simply that we have an observed phenomina (evolution) which occurs through a well-described, observed, and understood mechanism. One of the products of this process is the accumulation of genetic material, resulting in increasingly complex organisms.
You (by which I mean creationists) do not like what that implies for your literalistic interpretation of the bible. As such you've tried to re-define evolution into two groups - one group which you want to be false (increasing complexity) and one which you'll conede as it doesn't harm your faith too much.
Problem is, those two things are not separatable. The former (large-scale changes) is mearly the product of the later (small-scale changes) occuring over long periods of time. Likewise, all of the events along that road are known to occur - increases in genetic material/complexity, mutations, selection, single cell to multicell transisitons, speciation, etc, etc, etc. Each and every one of those has been directly observed in nature and/or in the lab. Likewise, both the fossil and genomic record contains the expected "fossils" of that evolutionary process.
Bryan>>>>"PE is simply periods of faster-than-normal evolution."
Ok. I would even say that some articles seem to link that strict gradualists are still quite amazed how changes in species can occur so quickly. I'm just wondering why certain popular introductory college biology texts have no mention of it anymore. But I get what you are saying.
I'm curious which text you are looking at. As I mentioned earlier I do some university-level teaching, and the several text's I use to prepare my lectures do include PE as part of their section on evolution.
If I had to guess (and assuming you are right about "several popular" texts lack mention of PE) is that we no longer treat PE as something
special" or "different" in evolution. Evolution simply does not go at one set speed, PE just happens to be the name given wqhen "high gear" was first noticed.
Bryan>>>>"It is that "random" change in gene frequqncies that is drift."
Sure, the bottleneck effect and the founder effect...
No, those arequite different. Bottlenecks occur as a result of intense selection, not an absence of selection. Founder effects is a consiquence of a bottle neck - you can only work with what makes it through the period of intense selection.
Genetic drift is also dependent upon small population sizes because the liklihood of some random characteristic becoming the abundant characteristic increases...
Actually, you can get drift in large populations. A new gene/allele does not need to spread through an entier population to "drift" - all it has to do is be inherited. For example, lets say you have 2 kids, and pass on one of your 4 point mutations to both. The frequency of your new mutation has just gone from 1:3,00,000 to 1:1,000,000; and as such has undergone drift as its frequecy in the population has now increased.
I get all that. But genetic drift does not introduce new genes, it only acts on the already present genes. Therefore it has not role in the discussion of how a single celled prokaryote evolved into a human via mutations of the DNA over millions of years (billions...3 or so actually)
Drift does not produce new genes, that much is true. But it has most certnatly played a central role in the evolution of humans. After all, drift plays a role in determining which genes/allels are present when selection occurs. Without drift there would have been different mixtures of genes/alleles present at times of selection, and thus, different outcomes would have been possible. Who knows how many times drift enriched alleles that were needed to make humans, or reduced alleles that would have led us down a different evolutionary path.
Bryan>>>>"That is not a definition of evolution. Evolution (biological evolution) is one of two things:
1) Evolution is a physical, obervable process that results in heritable changes in a population spread over many generations
2) A scientific thoery which describes why we see #1 occuring"
So according to #1, evolution is the directly observed change in allelic frequencies of organisms over time. And #2 is the theory of how it happens (the possible label of neo-Darwinism could be used here).
You've still got #1 wrong. Changes in allelic frequency arebut one possible outcome of evolution, amoung at least a dozen other possible outcomes. Heritable changes are more then justchanges in allele frrequency - it also involves making new alleles/genes, deleting alleles/genes, reorganizing the gemone, changing gene expression, and much, much more. All of those togeather are evoltuion, changes in allele frequency is just one tiny part of a much larger process.
So since #1 limits us to directly observable phenomena. I get it. I actually prefer it. And if that was the case, the debate, from my point of view, would be over.
Only if you restrict yourself to the very limited range of obsrevations you seem to think we have made. The reality is that every step required to convert a single-celled organism into a human has been observed to occur - mutations, new genes/alleles, unicellular to multicellula transitions, speciation, etc.
The directly observed phenomina alone speak greatly towards the progression of single-celled life to man; the fact that inferred evidence - fossil records, genenetic analysis, etc, etc, etc, fit in perfectly with the directly observed evidence addsyet more credance to the argument.
Bryan>>>>"That said, the process of unicellular life giving rise to mutlicellular life is a near-certanty, and is well supported by a large host of evidence. We've even observed the change from unicellularity to multicellularity in the lab (in C. vulgaris)."
Can you give a "layman's" account of this? Possibly a document that I could read?
I don't know about a laymans description; I've only ever seen scientific articles on the subject. The initial study, where the event was observed:
Boraas, M. E. 1983. Predator induced evolution in chemostat culture. EOS. Transactions of the American Geophysical Union. 64:1102.
Here's my best whack at it.
Boraas was growing Chlorella pyrenoidosa in culture, as food for the organism he was actually interested in (Ochromonas). Due to a equipment failiure the Ochromonas ended up mixing (by accident) into the tank being used to grow Chlorella. Within a few days the Chlorella began living as colonies too large to be consumed. Over time these colonies developed into a 8-cell organism. This organism always contained 8 cells, reproduces in a multicellular fashion (i.e. one cell doesn't just bud off and form a new colony; rather, the colony duplicates as a whole), and cannot not survive as single cells. This new multicelllular organism is now known to be a new species (C. vulgaris), and hass been stabally growing for over 20 years (equievelent to ~17,800 generations).
It sounds like an awesome experiement. Understand that I have no direct access to database journals or subscriptions so if you could reference something that "everybody" could reach, that would be great. Again, it sounds like a fascinating experiment!
It is a facanating accident that we were lucky to catch (I cannot count the number of times I've thrown away a contaminated culture; who knows what I have missed?). . I'll look to see if I can find a laymans source that describes thing in detail. That said, I think the origonal article is available free, in PDF form, from TAGU
Bryan