It's tough.
I live 3 hours from MHC/Beaufort NC and have a place to stay year round. If I go down for a week, I assume I'll get out 3 days out of 7, sometimes more, sometimes not at all.
When it's good, NC wreck diving is the second best salt water wreck diving worldwide after Truk Lagoon. Red Sea is a close third. IMHO.
400 years of bad weather, tricky navigation and two world wars makes the NC coast a helluva wreck diving location.
2 hour rides in 3-5 ft seas are common. My observations are about 20% of passengers get seasick. Sometimes the mates are a little green as well.
Some Captains claim that the boat and crew will handle 7 ft seas. I did this once and thankfully we turned around when reported visibility at the U352 was 1 ft.
Sometimes the seas are slick as a lake, visibility is gin clear and there's no current. Those are the days I live for.
Mike