Deeper than 60, and especially at 100, mistakes that might be annoying at 20-40 ft. become dangerous.
Diving deeper demands that you:
Be in control of your buoyancy
Be aware of your time, depth, NDL, and breathing gas pressure
Have a dive plan that returns you to the surface with a gas reserve
Have a redundant breathing gas supply (reliable buddy or self-carried)
Plan to make a safety stop
Have an emergency plan including available Oxygen and emergency phone numbers
Preferably be a member of DAN so you are insured should an accident occur
Dive safe, and enjoy the deep,
theskull