...while I'm not a reg expert.....I do own half a dozen Jetstreams (although I'll admit I don't really dive them anymore....they've been reliable and fine performance, but parts/service has sometimes been expensive/few techs service them and know what they're doing 'setting them up') and I'd assume any recent model Jetstream will be good out of the box for up to 40% nitrox...which is the 'standard' ceiling percentage before it's considered going into the 'tech' realm of O2 mixes. Jetstreams only come in one version, not an 'air' vs 'nitrox' version.....however, if you're buying an older/used one...since it will need a 'service' anyway, just to be safe, you can make sure the reg tech installs the appropriate material/type of O-rings to make sure it is compatable with 'high' percentages of oxygen. Also, if you're planning to go 'tech', you will likely need multiple sets of regs........recreational reg/regs for diving 'air' or nitrox mixes below 40%...and 'tech' regs for higher than 40% nitrox mixes/trimix, as 'tech' regs need to be kept 'oxygen-clean' to safely use 'tech' mixes......if you take an 'oxygen-clean' reg and use it once on a tank of gas which doesn't meet 'hyper-clean' standards...your 'tech' reg is now 'dirty/contaminated' and you will have to pay a reg tech to tear the whole reg set down, oxygen-clean it, and reassemble it before you can safely use it with a 'tech' gas mix.