ElectricZombie once bubbled...
The R380 is a great reg, that is what I use.
The R380 is easy to adjust, simple and reliable.
I'll second that.
My purchase is going to be the Mk16/S550 with an R380 secondary, necklaced. The S550 will be on a 7' hose, Hogarthian style, as per DIR.
I like this setup because of the diaphragms everywhere instead of pistons. (And even a sealed first stage.) My experience is that they simply do better for mud, black water, and salt water, where I will be spending most of my time. I like the simpler design of the Mk16 over the Mk25, too, due to it's lack of the additional swivel, which IMHO is another failure point with no real benefit.
I also am a fan of LESS controls on a reg. I'd personally rather see a reg set up right from the LDS and have LESS controls on it. I'm not a fan of a "cracking pressure" adjustment. I know that sounds strange, but I'd rather have it set right and then left right, rather than make it adjustable.
The S550 and the R380 are the balanced and nonbalanced versions of the same reg. I like that idea. They're both getting lots of great reviews, cost considerably less than the Apeks competitor, and don't use funny hoses like the Apeks does. Oh yeah... At least around here, there's a lot more places that are qualified to work on Scubapro than Apeks, so there's a bit of an advantage to that, too.
So Yeah, I'm a fan of the 380. Simple, inexpensive, dependable, great performance, low price, and overall a great reg.
...And it's dry upside-down, too... An important characteristic to ask for when you make money scraping boats (upside-down).