I'm not an expert, but as I have heard it, the thinking goes that the barrel-oring design is more likely to suffer impacts (such as with an overhead) gently without causing catastrophic gas-loss.
Also, from a more pragmatic point of view, the isolator crossbar can rotate freely in a barrel-oring design and there is more tolerance in how the manifold fits together.
As a scientifically meaningless datapoint, I had a set of my doubles knocked off of a table at the dive site and they fell to the ground at a bad angle causing one tank to slip. This caused a very noticeable bend in the manifold (to the point where I thought twice about even touching the thing) but absolutely no gas leak. Granted nothing like that kind of impact is likely to happen underwater, but it's nice to know that it can survive that.