Hello @hiker11. I can't comment based on experience with DCS and PFOs, but I also have a lifelong history of migraines with occasional aura. Like the two of you now, I'm also a two-tank-per-day-max kind of "older diver".He also has a lifelong history of migraines, with occasional aura, which is often associated with PFOs.
No-one has touched on this so far so I just wanted to add that my personal rule is to scrub a dive morning if I have a headache, no matter how slight, because for me they can quickly escalate without warning, which causes all kinds of stress on my system that I just don't need underwater and could possibly contribute to DCI.
Roatan is just far enough away from where I live that I can't dive there as often as I would like, but it has the advantage of an on-island chamber with a good reputation, which only adds to its appeal for me as a dive destination. You didn't specify what you meant by "not too far from a chamber" but for me personally I would be uncomfortable with anything over an hour away from the dive site. Which yes, limits my choice of dive destinations considerably, especially when combined with my above rule about scrubbing a planned dive if I am suffering from something as simple as a minor headache.
I believe there are other dive destinations in the Caribbean with similar easy, quick access to a chamber. Unfortunately it probably no longer compares to the Pacific in terms of underwater beauty (and perhaps never did), but I will take what I can get...